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8W1L

Structure of CSF1R kinase domain in complex with Cpd 32

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMacrophage colony-stimulating factor 1 receptor,CSF1Rpolymer33337850.31UniProt (P07333)
Pfam (PF07714)
In PDB
Homo sapiens (human)CSF-1 receptor,CSF-1-R,CSF-1R,M-CSF-R,Proto-oncogene c-Fms
2A[3-({3-methoxy-4-[(6-methoxypyridin-3-yl)methoxy]phenyl}methyl)-3H-imidazo[4,5-b]pyridin-6-yl](2-oxa-6-azaspiro[3.3]heptan-6-yl)methanonenon-polymer501.51Chemie (A1AE3)
3AGLYCEROLnon-polymer92.11Chemie (GOL)
4ASULFATE IONnon-polymer96.12Chemie (SO4)
5waterwater18.077Chemie (HOH)
Sequence modifications
A: 538 - 678 (UniProt: P07333)
PDBExternal DatabaseDetails
Gly 537-expression tag
A: 732 - 773 (PDB: 8W1L)
A: 774 - 922 (UniProt: P07333)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37850.3
Non-Polymers*Number of molecules4
Total formula weight785.8
All*Total formula weight38636.0
*Water molecules are not included.

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PDB entries from 2024-07-17

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