8W1L
Structure of CSF1R kinase domain in complex with Cpd 32
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Macrophage colony-stimulating factor 1 receptor,CSF1R | polymer | 333 | 37850.3 | 1 | UniProt (P07333) Pfam (PF07714) | Homo sapiens (human) | CSF-1 receptor,CSF-1-R,CSF-1R,M-CSF-R,Proto-oncogene c-Fms |
| 2 | B (A) | [3-({3-methoxy-4-[(6-methoxypyridin-3-yl)methoxy]phenyl}methyl)-3H-imidazo[4,5-b]pyridin-6-yl](2-oxa-6-azaspiro[3.3]heptan-6-yl)methanone | non-polymer | 501.5 | 1 | Chemie (A1AE3) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F (A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 538 - 678 (UniProt: P07333)
A: 732 - 773 (PDB: 8W1L)
A: 774 - 922 (UniProt: P07333)
| PDB | External Database | Details |
|---|---|---|
| Gly 537 | - | expression tag |
A: 774 - 922 (UniProt: P07333)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37850.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 785.8 | |
| All* | Total formula weight | 38636.0 |
