8W1A

Cryo-EM Structure of KSHV ORF74 Apo Dimer at 2.8A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	viral G-protein coupled receptor	polymer	369	42132.3	2	UniProt (Q98146) Pfam (PF00001)	Human gammaherpesvirus 8	vGPCR,Protein ORF74

Sequence modifications

A, B: 1 - 340 (UniProt: Q98146)

PDB	External Database	Details
Trp 169	Leu 169	engineered mutation
Val 258	Leu 258	engineered mutation
Asp 341	-	expression tag
Tyr 342	-	expression tag
Lys 343	-	expression tag
Asp 344	-	expression tag
Asp 345	-	expression tag
Asp 346	-	expression tag
Asp 347	-	expression tag
Lys 348	-	expression tag
Gly 349	-	expression tag
Arg 350	-	expression tag
Pro 351	-	expression tag
Leu 352	-	expression tag
Glu 353	-	expression tag
Val 354	-	expression tag
Leu 355	-	expression tag
Phe 356	-	expression tag
Gln 357	-	expression tag
Gly 358	-	expression tag
Pro 359	-	expression tag
His 360	-	expression tag
His 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84264.5
All*	Total formula weight	84264.5

*Water molecules are not included.