8W1A
Cryo-EM Structure of KSHV ORF74 Apo Dimer at 2.8A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006955 | biological_process | immune response |
| A | 0007165 | biological_process | signal transduction |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| A | 0016493 | molecular_function | C-C chemokine receptor activity |
| A | 0019722 | biological_process | calcium-mediated signaling |
| A | 0019957 | molecular_function | C-C chemokine binding |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0060326 | biological_process | cell chemotaxis |
| A | 0070098 | biological_process | chemokine-mediated signaling pathway |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006955 | biological_process | immune response |
| B | 0007165 | biological_process | signal transduction |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| B | 0016493 | molecular_function | C-C chemokine receptor activity |
| B | 0019722 | biological_process | calcium-mediated signaling |
| B | 0019957 | molecular_function | C-C chemokine binding |
| B | 0020002 | cellular_component | host cell plasma membrane |
| B | 0060326 | biological_process | cell chemotaxis |
| B | 0070098 | biological_process | chemokine-mediated signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 94 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 126 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
