8W18
The crystal structure of the Michaelis-Menten complex of a C1s/C1-INH at 3.94 Angstroms
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | I | Plasma protease C1 inhibitor | polymer | 395 | 43997.4 | 1 | UniProt (P05155) Pfam (PF00079) In PDB | Homo sapiens (human) | C1 Inh,C1Inh,C1 esterase inhibitor,C1-inhibiting factor,Serpin G1 |
2 | B | Complement C1s subcomponent light chain | polymer | 251 | 27668.5 | 1 | UniProt (P09871) Pfam (PF00089) In PDB | Homo sapiens (human) | |
3 | A | Complement C1s subcomponent heavy chain | polymer | 151 | 16588.5 | 1 | UniProt (P09871) Pfam (PF00084) In PDB | Homo sapiens (human) |
Sequence modifications
I: 111 - 500 (UniProt: P05155)
B: 438 - 688 (UniProt: P09871)
A: 292 - 437 (UniProt: P09871)
PDB | External Database | Details |
---|---|---|
Gly 106 | - | expression tag |
Ser 107 | - | expression tag |
Thr 108 | - | expression tag |
Gly 109 | - | expression tag |
Ser 110 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 632 | Ser 632 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 287 | - | expression tag |
Ser 288 | - | expression tag |
Thr 289 | - | expression tag |
Gly 290 | - | expression tag |
Ser 291 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 88254.5 | |
All* | Total formula weight | 88254.5 |