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8W0Y

Crystal structure of broadly neutralizing antibody hcab17 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, H)
hcab17 Fab Heavy Chainpolymer23625217.12Homo sapiens
2B, F
(B, L)
hcab17 Fab Light Chainpolymer21423392.02Homo sapiens
3C, D
(C, D)
Envelope glycoprotein E2polymer26228946.52UniProt (A0A2P0NE15)
UniProt (by SIFTS) (A0A2P0NE26)
Hepacivirus hominis
4G, H, J, L, M...
(E, F, I, K, M...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.47In PDB
GlyTouCan (G42666HT)
5I
(G)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
6K, N
(J, N)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
7Q
(C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
8R, S, T
(A, C, D)
waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight155111.2
BranchedNumber of molecules10
Total formula weight5054.7
Non-Polymers*Number of molecules1
Total formula weight221.2
All*Total formula weight160387.1
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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