8W0R

Human EBP complexed with compound 1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	polymer	238	27421.9	2	UniProt (Q15125) Pfam (PF05241) In PDB	Homo sapiens (human)	Cholestenol Delta-isomerase,Delta(8)-Delta(7) sterol isomerase,D8-D7 sterol isomerase,Emopamil-binding protein, EBP
2	A, B	1-methyl-1'-[(oxan-4-yl)methyl]-5-(trifluoromethyl)spiro[indole-2,4'-piperidin]-3(1H)-one	non-polymer		382.4	2	Chemie (A1AEU)

Sequence modifications

A, B: 2 - 230 (UniProt: Q15125)

PDB	External Database	Details
Met -7	-	initiating methionine
Trp -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag
Pro -3	-	expression tag
Gln -2	-	expression tag
Phe -1	-	expression tag
Glu 0	-	expression tag
Lys 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54843.7
Non-Polymers*	Number of molecules	2
	Total formula weight	764.8
All*	Total formula weight	55608.6

*Water molecules are not included.