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8W0R

Human EBP complexed with compound 1

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000247molecular_functionC-8 sterol isomerase activity
A0004769molecular_functionsteroid delta-isomerase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0006695biological_processcholesterol biosynthetic process
A0008203biological_processcholesterol metabolic process
A0016020cellular_componentmembrane
A0016125biological_processsterol metabolic process
A0016126biological_processsterol biosynthetic process
A0016787molecular_functionhydrolase activity
A0016853molecular_functionisomerase activity
A0030097biological_processhemopoiesis
A0031410cellular_componentcytoplasmic vesicle
A0031965cellular_componentnuclear membrane
A0033489biological_processcholesterol biosynthetic process via desmosterol
A0033490biological_processcholesterol biosynthetic process via lathosterol
A0033963molecular_functioncholesterol-5,6-oxide hydrolase activity
A0042802molecular_functionidentical protein binding
A0043931biological_processossification involved in bone maturation
A0047750molecular_functioncholestenol delta-isomerase activity
B0000247molecular_functionC-8 sterol isomerase activity
B0004769molecular_functionsteroid delta-isomerase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005635cellular_componentnuclear envelope
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0006695biological_processcholesterol biosynthetic process
B0008203biological_processcholesterol metabolic process
B0016020cellular_componentmembrane
B0016125biological_processsterol metabolic process
B0016126biological_processsterol biosynthetic process
B0016787molecular_functionhydrolase activity
B0016853molecular_functionisomerase activity
B0030097biological_processhemopoiesis
B0031410cellular_componentcytoplasmic vesicle
B0031965cellular_componentnuclear membrane
B0033489biological_processcholesterol biosynthetic process via desmosterol
B0033490biological_processcholesterol biosynthetic process via lathosterol
B0033963molecular_functioncholesterol-5,6-oxide hydrolase activity
B0042802molecular_functionidentical protein binding
B0043931biological_processossification involved in bone maturation
B0047750molecular_functioncholestenol delta-isomerase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues160
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
ATRP29-LEU49
ALEU66-TYR86
AMET121-LEU141
APHE185-LEU205
BTRP29-LEU49
BLEU66-TYR86
BMET121-LEU141
BPHE185-LEU205

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylthreonine => ECO:0007744|PubMed:25944712
ChainResidueDetails
ATHR2
BTHR2

229681

PDB entries from 2025-01-08

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