8VZZ
Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinol-binding protein 2 | polymer | 133 | 15689.6 | 2 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | C, F (A, B) | (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal | non-polymer | 271.4 | 2 | Chemie (A1AEQ) | |||
| 3 | D, E, G, H (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Trp 19 | Tyr 20 | engineered mutation |
| Leu 40 | Lys 41 | engineered mutation |
| Val 51 | Thr 52 | engineered mutation |
| Ser 53 | Thr 54 | engineered mutation |
| Trp 58 | Arg 59 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
| Gln 112 | Gly 113 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31379.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 778.9 | |
| All* | Total formula weight | 32158.2 |
