8VZC

Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthse ApbHACS from Alphaproteobacteria bacterium in the Complex with THDP, Formyl-CoA, and ADP

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Oxalyl-CoA decarboxylase	polymer	557	59512.7	4	UniProt (A0A3C0TX30) Pfam (PF02776) Pfam (PF00205) Pfam (PF02775)	Alphaproteobacteria bacterium
2	E, EA, O, V (A, D, B, C)	3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-(hydroxymethyl)-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium	non-polymer		455.3	4	Chemie (A1AEK)
3	F, FA, P, W (A, D, B, C)	S-{(9R,13S,15R)-17-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-9,13,15-TRIHYDROXY-10,10-DIMETHYL-13,15-DIOXIDO-4,8-DIOXO-12,14,16-TRIOXA-3,7-DIAZA-13,15-DIPHOSPHAHEPTADEC-1-YL} THIOFORMATE	non-polymer		795.5	4	Chemie (FYN)
4	G, GA, Q, X (A, D, B, C)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	H, HA, R, Y (A, D, B, C)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)
6	AA, BA, CA, I, IA... (C, A, D, B)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
7	DA, KA, N, U (C, D, A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
8	Z (C)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
9	LA, MA, NA, OA (A, B, C, D)	water	water		18.0	2063	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 554 (UniProt: A0A3C0TX30)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	238050.9
Non-Polymers*	Number of molecules	33
	Total formula weight	8040.4
All*	Total formula weight	246091.3

*Water molecules are not included.