8VX4

Human OGG1 bound to a 35-bp DNA with an 8-oxoG in the middle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	DNA (35-MER)	polymer	35	10695.9	1		synthetic construct
2	B (B)	DNA (35-MER)	polymer	35	10861.9	1		synthetic construct
3	C (A)	N-glycosylase/DNA lyase	polymer	387	43720.0	1	UniProt (O15527) Pfam (PF07934) Pfam (PF00730)	Homo sapiens (human)

Sequence modifications

A: 2 - 345 (UniProt: O15527)

PDB	External Database	Details
Met -41	-	expression tag
Gly -40	-	expression tag
His -39	-	expression tag
His -38	-	expression tag
His -37	-	expression tag
His -36	-	expression tag
His -35	-	expression tag
His -34	-	expression tag
Asp -33	-	expression tag
Tyr -32	-	expression tag
Lys -31	-	expression tag
Asp -30	-	expression tag
His -29	-	expression tag
Asp -28	-	expression tag
Gly -27	-	expression tag
Asp -26	-	expression tag
Tyr -25	-	expression tag
Lys -24	-	expression tag
Asp -23	-	expression tag
His -22	-	expression tag
Asp -21	-	expression tag
Ile -20	-	expression tag
Asp -19	-	expression tag
Tyr -18	-	expression tag
Lys -17	-	expression tag
Asp -16	-	expression tag
Asp -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Lys -12	-	expression tag
Glu -11	-	expression tag
Asn -10	-	expression tag
Leu -9	-	expression tag
Tyr -8	-	expression tag
Phe -7	-	expression tag
Gln -6	-	expression tag
Gly -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asp 1	-	expression tag
Gln 249	Lys 249	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65277.8
All*	Total formula weight	65277.8

*Water molecules are not included.