8VX4
Human OGG1 bound to a 35-bp DNA with an 8-oxoG in the middle
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Schiff-base intermediate with DNA => ECO:0000269|PubMed:9197244 |
| Chain | Residue | Details |
| A | GLN249 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10706276, ECO:0000269|PubMed:11902834, ECO:0000269|PubMed:12578369, ECO:0000269|PubMed:12592398, ECO:0000269|PubMed:15610848 |
| Chain | Residue | Details |
| A | ASN149 | |
| A | ARG154 | |
| A | ARG204 | |
| A | HIS270 | |
| A | GLN287 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PRO266 | |
| A | ASP268 | |
| A | GLN315 | |
| A | PHE319 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 185 |
| Chain | Residue | Details |
| A | GLN249 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ASP268 | electrostatic stabiliser, hydrogen bond acceptor |
