8VVY

Human Cullin-1 in complex with CAND2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cullin-1	polymer	741	86294.5	1	UniProt (Q13616) Pfam (PF00888) Pfam (PF26557) Pfam (PF10557)	Homo sapiens (human)	CUL-1
2	B (C)	Cullin-associated NEDD8-dissociated protein 2	polymer	1247	136669.5	1	UniProt (O75155) Pfam (PF13513) Pfam (PF25782) Pfam (PF08623)	Homo sapiens (human)	Cullin-associated and neddylation-dissociated protein 2,Epididymis tissue protein Li 169,TBP-interacting protein of 120 kDa B,TBP-interacting protein 120B,p120 CAND2

Sequence modifications

A: 2 - 741 (UniProt: Q13616)

PDB	External Database	Details
Ser 1	-	expression tag
-	Ser 59	deletion
-	Asn 60	deletion
-	Gln 61	deletion
-	Ala 62	deletion
-	Arg 63	deletion
-	Gly 64	deletion
-	Ala 65	deletion
-	Gly 66	deletion
-	Val 67	deletion
-	Pro 68	deletion
-	Pro 69	deletion
-	Ser 70	deletion
-	Lys 71	deletion
-	Ser 72	deletion
-	Lys 73	deletion
-	Lys 74	deletion
-	Gly 75	deletion
-	Gln 76	deletion
-	Thr 77	deletion
-	Pro 78	deletion
-	Gly 79	deletion
-	Gly 80	deletion
-	Ala 81	deletion
-	Gln 82	deletion

C: 12 - 1247 (UniProt: O75155)

PDB	External Database	Details
Ser 1	-	expression tag
Ala 2	-	expression tag
Gly 3	-	expression tag
Trp 4	-	expression tag
Ser 5	-	expression tag
His 6	-	expression tag
Pro 7	-	expression tag
Gln 8	-	expression tag
Phe 9	-	expression tag
Glu 10	-	expression tag
Lys 11	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	222964.0
All*	Total formula weight	222964.0

*Water molecules are not included.