8VVO

Structure of FabS1CE2-EPR1-1 in complex with the erythropoietin receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	S1CE2 VARIANT OF FAB-EPR-1 heavy chain	polymer	224	24022.9	2		Homo sapiens
2	G, C	S1CE2 VARIANT OF FAB-EPR-1 light chain	polymer	212	23049.5	2		Homo sapiens
3	I	Erythropoietin receptor	polymer	232	25680.0	1	UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB	Homo sapiens (human)	EPO-R
4	G	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5	C	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Sequence modifications

I: 1 - 226 (UniProt: P19235)

PDB	External Database	Details
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	119824.8
Non-Polymers*	Number of molecules	2
	Total formula weight	58.4
All*	Total formula weight	119883.2

*Water molecules are not included.