8VUX
Cryo-EM structure of human ABC transporter (hABCC1) bound to cGAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Multidrug resistance-associated protein 1 | polymer | 1531 | 171763.0 | 2 | UniProt (P33527) Pfam (PF00664) Pfam (PF00005) | Homo sapiens (human) | ATP-binding cassette sub-family C member 1,Glutathione-S-conjugate-translocating ATPase ABCC1,Leukotriene C(4) transporter,LTC4 transporter |
| 2 | C, E (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 3 | D (B) | cGAMP | non-polymer | 674.4 | 1 | Chemie (1SY) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 343525.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1647.9 | |
| All* | Total formula weight | 345173.8 |
