8VTC
Crystal structure of Mycobacterium avium dihydrofolate reductase in complex with NADPH and trimethoprim
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 167 | 18451.8 | 1 | UniProt (O30463) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) | Mycobacterium avium | |
| 2 | B (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | C (A) | TRIMETHOPRIM | non-polymer | 290.3 | 1 | Chemie (TOP) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18451.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1071.2 | |
| All* | Total formula weight | 19523.0 |
