8VR9
Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 278 | 32047.3 | 1 | UniProt (P04439) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | Human leukocyte antigen A,HLA-A |
| 2 | B (B) | Beta-2-microglobulin | polymer | 101 | 11892.3 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | GTPase KRas, N-terminally processed | polymer | 9 | 790.0 | 1 | UniProt (P01116) | Homo sapiens | |
| 4 | D (D) | R023 Fab light chain | polymer | 216 | 23518.2 | 1 | Homo sapiens | ||
| 5 | E (E) | R023 Fab heavy chain | polymer | 228 | 24034.8 | 1 | Homo sapiens | ||
| 6 | F (E) | AMG 510 (bound form) | non-polymer | 562.6 | 1 | Chemie (MOV) |
Sequence modifications
A: 1 - 275 (UniProt: P04439)
B: 21 - 119 (UniProt: P61769)
C: 8 - 16 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Cys 12 | Gly 12 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 92282.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 562.6 | |
| All* | Total formula weight | 92845.2 |
