8VQ2
HSV1 polymerase ternary complex with dsDNA and compound 44
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA polymerase | polymer | 1163 | 129637.0 | 2 | UniProt (I7GY94) Pfam (PF03104) Pfam (PF00136) In PDB | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | |
2 | C, E | DNA (5'-D(P*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*T)-3') | polymer | 15 | 4754.1 | 2 | synthetic construct | ||
3 | D, F | DNA (5'-D(P*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3') | polymer | 13 | 3822.5 | 2 | synthetic construct | ||
4 | C, E | 2-(4-bromophenyl)-N-(3-methoxy-4-{[(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl}phenyl)acetamide | non-polymer | 419.3 | 2 | Chemie (A1AC6) |
Sequence modifications
A, B: 43 - 1197 (UniProt: I7GY94)
PDB | External Database | Details |
---|---|---|
Leu 35 | - | expression tag |
Glu 36 | - | expression tag |
Val 37 | - | expression tag |
Leu 38 | - | expression tag |
Phe 39 | - | expression tag |
Gln 40 | - | expression tag |
Gly 41 | - | expression tag |
Pro 42 | - | expression tag |
Ala 370 | Glu 370 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 276427.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 838.5 | |
All* | Total formula weight | 277265.6 |