8VL7
Co-crystal structure of human TREX1 in complex with an inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Three-prime repair exonuclease 1 | polymer | 233 | 25032.8 | 8 | UniProt (Q9NSU2) | Homo sapiens (human) | 3'-5' exonuclease TREX1,Deoxyribonuclease III,DNase III |
| 2 | AA, EA, I, IA, MA... (E, F, A, G, H...) | (2P)-2-[3-bromo-2-(2-hydroxyethoxy)phenyl]-5-hydroxy-1-methyl-N-(1,2-oxazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide | non-polymer | 451.2 | 8 | Chemie (A1ACJ) | |||
| 3 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | BA, CA, FA, GA, JA... (E, F, G, A, H...) | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
| 5 | HA, LA, M, N, R (F, G, A, B) | UNKNOWN ATOM OR ION | non-polymer | 5 | Chemie (UNX) | ||||
| 6 | DA, V (E, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 7 | W (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | PA, QA, RA, SA, TA... (A, B, C, D, E...) | water | water | 18.0 | 449 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 200262.1 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 4585.4 | |
| All* | Total formula weight | 204847.5 |
