8VKH

Structure of gelsolin domains G1G3 bound to the barbed end of F-actin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Actin, alpha skeletal muscle	polymer	375	41875.6	6	UniProt (P68135) Pfam (PF00022)	Oryctolagus cuniculus (rabbit)	Alpha-actin-1
2	G, H (G, H)	Gelsolin	polymer	745	82606.5	2	UniProt (P06396) Pfam (PF00626)	Homo sapiens (human)	AGEL,Actin-depolymerizing factor,ADF,Brevin
3	I, K, M, O (A, B, C, D)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)
4	AA, BA, J, L, N... (H, A, B, C, D...)	CALCIUM ION	non-polymer		40.1	14	Chemie (CA)
5	Q, S (E, F)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)

Sequence modifications

G, H: 25 - 755 (UniProt: P06396)

PDB	External Database	Details
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
Trp 756	-	expression tag
Ser 757	-	expression tag
His 758	-	expression tag
Pro 759	-	expression tag
Gln 760	-	expression tag
Phe 761	-	expression tag
Glu 762	-	expression tag
Lys 763	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	416466.8
Non-Polymers*	Number of molecules	20
	Total formula weight	3284.3
All*	Total formula weight	419751.0

*Water molecules are not included.