8VKA
Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 9c
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glycylpeptide N-tetradecanoyltransferase | polymer | 386 | 45100.6 | 3 | UniProt (A5K1A2) Pfam (PF01233) Pfam (PF02799) | Plasmodium vivax Sal-1 | |
| 2 | CA, D, U (C, A, B) | TETRADECANOYL-COA | non-polymer | 977.9 | 3 | Chemie (MYA) | |||
| 3 | DA, E, V (C, A, B) | N-[1,5-dimethyl-4-(2-{[(2M)-2'-(piperazin-1-yl)[2,4'-bipyridin]-3-yl]oxy}ethyl)-1H-pyrazole-3-carbonyl]glycine | non-polymer | 479.5 | 3 | Chemie (A1AB7) | |||
| 4 | EA, F, FA, G, GA... (C, A, B) | CHLORIDE ION | non-polymer | 35.5 | 24 | Chemie (CL) | |||
| 5 | BA, LA, S (B, C, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | MA, T (C, A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 7 | AA (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | NA (C) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 1 | Chemie (P33) | |||
| 9 | OA, PA, QA (A, B, C) | water | water | 18.0 | 951 | Chemie (HOH) |
Sequence modifications
A, B, C: 27 - 410 (UniProt: A5K1A2)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 135301.7 | |
| Non-Polymers* | Number of molecules | 37 |
| Total formula weight | 6326.7 | |
| All* | Total formula weight | 141628.4 |
