8VJ7
GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform Flip of Glutamate receptor 2 | polymer | 797 | 89233.0 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, G, I, K (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
| 3 | F, H, J, L (A, C, D) | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline | non-polymer | 293.3 | 4 | Chemie (A1AB5) |
Sequence modifications
A, B, C, D: 10 - 821 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Glu 241 | Asn 256 | conflict |
| Leu 382 | Val 397 | conflict |
| - | Leu 399 | deletion |
| - | Thr 400 | deletion |
| - | Glu 401 | deletion |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| Glu 384 | Gly 405 | conflict |
| Asp 385 | Asn 406 | conflict |
| Gln 392 | Asn 413 | conflict |
| - | Glu 571 | deletion |
| - | Trp 572 | deletion |
| - | His 573 | deletion |
| - | Thr 574 | deletion |
| - | Glu 575 | deletion |
| - | Glu 576 | deletion |
| - | Phe 577 | deletion |
| - | Glu 578 | deletion |
| - | Asp 579 | deletion |
| - | Gly 580 | deletion |
| - | Arg 581 | deletion |
| - | Glu 582 | deletion |
| - | Thr 583 | deletion |
| - | Gln 584 | deletion |
| - | Ser 585 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 356931.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1761.8 | |
| All* | Total formula weight | 358693.6 |
