8VJ7
GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 2
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Isoform Flip of Glutamate receptor 2 | polymer | 797 | 89233.0 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
2 | A, B, C, D | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) | |||
3 | A, C, D | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline | non-polymer | 293.3 | 4 | Chemie (A1AB5) |
Sequence modifications
A, B, C, D: 10 - 821 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Glu 241 | Asn 256 | conflict |
Leu 382 | Val 397 | conflict |
- | Leu 399 | deletion |
- | Thr 400 | deletion |
- | Glu 401 | deletion |
- | Leu 402 | deletion |
- | Pro 403 | deletion |
- | Ser 404 | deletion |
Glu 384 | Gly 405 | conflict |
Asp 385 | Asn 406 | conflict |
Gln 392 | Asn 413 | conflict |
- | Glu 571 | deletion |
- | Trp 572 | deletion |
- | His 573 | deletion |
- | Thr 574 | deletion |
- | Glu 575 | deletion |
- | Glu 576 | deletion |
- | Phe 577 | deletion |
- | Glu 578 | deletion |
- | Asp 579 | deletion |
- | Gly 580 | deletion |
- | Arg 581 | deletion |
- | Glu 582 | deletion |
- | Thr 583 | deletion |
- | Gln 584 | deletion |
- | Ser 585 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 356931.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1761.8 | |
All* | Total formula weight | 358693.6 |