8VG0
Cryo-EM structure of GATA4 in complex with ALBN1 nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (I) | DNA (159-MER) | polymer | 186 | 57399.6 | 1 | synthetic construct | ||
| 2 | B (J) | DNA (159-MER) | polymer | 186 | 57427.8 | 1 | synthetic construct | ||
| 3 | C, G (A, E) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 4 | D, H (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 5 | E, I (C, G) | Histone H2A type 1-B/E | polymer | 130 | 14165.6 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 6 | F, J (D, H) | Histone H2B type 1-J | polymer | 126 | 13935.2 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 7 | K (T) | Maltose/maltodextrin-binding periplasmic protein,Transcription factor GATA-4 | polymer | 835 | 87880.3 | 1 | UniProt (P0AEX9) UniProt (P43694) Pfam (PF01547) Pfam (PF05349) Pfam (PF00320) | Homo sapiens (human) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,GATA-binding factor 4 |
| 8 | L (T) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
T: -378 - -13 (UniProt: P0AEX9)
T: 1 - 442 (UniProt: P43694)
| PDB | External Database | Details |
|---|---|---|
| Met -392 | - | initiating methionine |
| Gly -391 | - | expression tag |
| Ser -390 | - | expression tag |
| Ser -389 | - | expression tag |
| His -388 | - | expression tag |
| His -387 | - | expression tag |
| His -386 | - | expression tag |
| His -385 | - | expression tag |
| His -384 | - | expression tag |
| His -383 | - | expression tag |
| Gly -382 | - | expression tag |
| Ser -381 | - | expression tag |
| Ser -380 | - | expression tag |
| Met -379 | - | expression tag |
| Asn -12 | - | linker |
| Gly -11 | - | linker |
| Ile -10 | - | linker |
| Glu -9 | - | linker |
| Glu -8 | - | linker |
| Asn -7 | - | linker |
| Leu -6 | - | linker |
| Tyr -5 | - | linker |
| Phe -4 | - | linker |
| Gln -3 | - | linker |
| Ser -2 | - | linker |
| Asn -1 | - | linker |
| Ala 0 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 312572.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 312637.8 |
