8VC3
Voltage gated potassium ion channel Kv1.2 in complex with DTx
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Kunitz-type serine protease inhibitor homolog alpha-dendrotoxin | polymer | 59 | 7015.1 | 1 | UniProt (P00980) In PDB | Dendroaspis angusticeps | Alpha-DTX,Protease inhibitor 1 homolog,Toxin C13S2C3,Venom basic protease inhibitor 1 homolog |
| 2 | E, B, C, D | Potassium voltage-gated channel subfamily A member 2 | polymer | 536 | 60591.6 | 4 | UniProt (P63142) In PDB | Rattus norvegicus (Rat) | RAK,RBK2,RCK5,Voltage-gated potassium channel subunit Kv1.2 |
| 3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) |
Sequence modifications
A: 2 - 59 (UniProt: P00980)
E, B, C, D: 1 - 499 (UniProt: P63142)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -36 | - | initiating methionine |
| Ser -35 | - | expression tag |
| Ala -34 | - | expression tag |
| Trp -33 | - | expression tag |
| Ser -32 | - | expression tag |
| His -31 | - | expression tag |
| Pro -30 | - | expression tag |
| Gln -29 | - | expression tag |
| Phe -28 | - | expression tag |
| Glu -27 | - | expression tag |
| Lys -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Ala -14 | - | expression tag |
| Trp -13 | - | expression tag |
| Ser -12 | - | expression tag |
| His -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Gln -9 | - | expression tag |
| Phe -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Lys -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 15 | Leu 15 | conflict |
| Ser 198 | Gly 198 | conflict |
| Gln 207 | Asn 207 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 249381.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 78.2 | |
| All* | Total formula weight | 249459.6 |
