8VBW
Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Penicillin-binding protein 1 | polymer | 595 | 66644.3 | 2 | UniProt (Q2FZ94) Pfam (PF03717) Pfam (PF00905) In PDB | Staphylococcaceae bacterium | |
2 | A, B | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 477.5 | 2 | Chemie (1RG) | |||
3 | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A, B: 39 - 608 (UniProt: Q2FZ94)
PDB | External Database | Details |
---|---|---|
Met 14 | - | initiating methionine |
Gly 15 | - | expression tag |
Ser 16 | - | expression tag |
Ser 17 | - | expression tag |
His 18 | - | expression tag |
His 19 | - | expression tag |
His 20 | - | expression tag |
His 21 | - | expression tag |
His 22 | - | expression tag |
His 23 | - | expression tag |
His 24 | - | expression tag |
His 25 | - | expression tag |
His 26 | - | expression tag |
His 27 | - | expression tag |
Ser 28 | - | expression tag |
Ser 29 | - | expression tag |
Gly 30 | - | expression tag |
Leu 31 | - | expression tag |
Val 32 | - | expression tag |
Pro 33 | - | expression tag |
Arg 34 | - | expression tag |
Gly 35 | - | expression tag |
Ser 36 | - | expression tag |
His 37 | - | expression tag |
Met 38 | - | expression tag |
Asp 118 | Asn 118 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 133288.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 955.1 | |
All* | Total formula weight | 134243.6 |