8V9Q
Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Polypeptide N-acetylgalactosaminyltransferase 1 soluble form | polymer | 559 | 64340.9 | 2 | UniProt (O08912) Pfam (PF00535) Pfam (PF00652) In PDB | Mus musculus (house mouse) | |
2 | D, F, H | Mucin-5AC | polymer | 16 | 1501.6 | 3 | UniProt (P98088) In PDB | Homo sapiens | MUC-5AC,Gastric mucin,Major airway glycoprotein,Mucin-5 subtype AC,tracheobronchial,Tracheobronchial mucin,TBM |
3 | X | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
4 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | A | SUCCINIC ACID | non-polymer | 118.1 | 1 | Chemie (SIN) | |||
8 | A, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
9 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
10 | D, F, H | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 3 | Chemie (A2G) | |||
11 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
12 | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 133186.6 | |
Branched | Number of molecules | 2 |
Total formula weight | 1335.2 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 2636.9 | |
All* | Total formula weight | 137158.7 |