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8V5L

Structure of the Varicella Zoster Virus (VZV) gI binding domain of glycoprotein E (gE) in complex with human Fab 1A2 and 1E12

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Fab 1A2 Heavy Chainpolymer24326711.81Homo sapiens (human)
2B
(L)
Fab 1A2 Light Chainpolymer21423477.01Homo sapiens (human)
3C
(A)
Envelope glycoprotein Epolymer20323281.01UniProt (Q77JX0)
Pfam (PF20418)
UniProt (by SIFTS) (A6XEF7)
Human alphaherpesvirus 3 (Varicella-zoster virus)
4D
(B)
Fab 1E12 Heavy Chainpolymer24826685.71Homo sapiens (human)
5E
(C)
Fab 1E12 Light Chainpolymer21923434.81Homo sapiens (human)
Sequence modifications
A: 116 - 307 (UniProt: Q77JX0)
PDBExternal DatabaseDetails
Glu 308-expression tag
Asn 309-expression tag
Leu 310-expression tag
Tyr 311-expression tag
Phe 312-expression tag
Gln 313-expression tag
Gly 314-expression tag
His 315-expression tag
His 316-expression tag
His 317-expression tag
His 318-expression tag
His 319-expression tag
His 320-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight123590.4
All*Total formula weight123590.4
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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