8V4X
Structure of MALT1 in complex with an allosteric inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | polymer | 387 | 43859.4 | 6 | UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703) In PDB | Homo sapiens (human) | MALT lymphoma-associated translocation,Paracaspase |
| 2 | G, H, I, J, K... | Inhibitor peptide | polymer | 6 | 697.2 | 6 | BIRD (PRD_001076) | synthetic construct | |
| 3 | A, B, C, D | N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea | non-polymer | 478.5 | 4 | Chemie (A1AAB) | |||
| 4 | water | water | 18.0 | 388 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 334 - 719 (UniProt: Q9UDY8)
| PDB | External Database | Details |
|---|---|---|
| Ser 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 267339.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1913.8 | |
| All* | Total formula weight | 269253.5 |
