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8V4X

Structure of MALT1 in complex with an allosteric inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Mucosa-associated lymphoid tissue lymphoma translocation protein 1polymer38743859.46UniProt (Q9UDY8)
Pfam (PF00656)
Pfam (PF18703)
In PDB
Homo sapiens (human)MALT lymphoma-associated translocation,Paracaspase
2G, H, I, J, K...Inhibitor peptidepolymer6697.26BIRD (PRD_001076)synthetic construct
3A, B, C, DN-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]ureanon-polymer478.54Chemie (A1AAB)
4waterwater18.0388Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 334 - 719 (UniProt: Q9UDY8)
PDBExternal DatabaseDetails
Ser 333-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight267339.7
Non-Polymers*Number of molecules4
Total formula weight1913.8
All*Total formula weight269253.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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