8V4R

Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Acetyl-coenzyme A synthetase 2	polymer	686	75908.4	3	UniProt (Q8NJN3) Pfam (PF16177) Pfam (PF00501) Pfam (PF13193)	Candida albicans
2	D, H, K (A, B, C)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	3	Chemie (AMP)
3	E, I, L (A, B, C)	COENZYME A	non-polymer		767.5	3	Chemie (COA)
4	F (A)	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
5	G, J (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	M, N, O (A, B, C)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

A, B, C: 17 - 686 (UniProt: Q8NJN3)

PDB	External Database	Details
Met 1	-	initiating methionine
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Glu 10	-	expression tag
Asn 11	-	expression tag
Leu 12	-	expression tag
Tyr 13	-	expression tag
Phe 14	-	expression tag
Gln 15	-	expression tag
Gly 16	-	expression tag
Ala 403	Val 388	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	227725.2
Non-Polymers*	Number of molecules	9
	Total formula weight	3588.5
All*	Total formula weight	231313.7

*Water molecules are not included.