8UY0
Consensus olfactory receptor consOR2 bound to S-carvone and in complex with mini-Gs trimeric protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | consOR2 | polymer | 321 | 35898.6 | 1 | synthetic construct | ||
| 2 | B (N) | Nanobody 35 | polymer | 145 | 15931.7 | 1 | Lama glama | ||
| 3 | C (X) | miniGs399 | polymer | 261 | 30137.0 | 1 | UniProt (A0A804HIH4) Pfam (PF00503) UniProt (by SIFTS) (P63092) | Homo sapiens (human) | |
| 4 | D (Y) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 370 | 40786.6 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 5 | E (Z) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 6 | F (A) | (5S)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one | non-polymer | 150.2 | 1 | Chemie (0WU) |
Sequence modifications
X: 204 - 394 (UniProt: A0A804HIH4)
Y: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Glu -3 | - | expression tag |
| Val -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Gln 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Asn 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Lys 8 | - | expression tag |
| Thr 9 | - | expression tag |
| Glu 10 | - | expression tag |
| Asp 11 | - | expression tag |
| Gln 12 | - | expression tag |
| Arg 13 | - | expression tag |
| Asn 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Gln 19 | - | expression tag |
| Arg 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Lys 24 | - | expression tag |
| Lys 25 | - | expression tag |
| Ile 26 | - | expression tag |
| Glu 27 | - | expression tag |
| Lys 28 | - | expression tag |
| Gln 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Gln 31 | - | expression tag |
| Lys 32 | - | expression tag |
| Asp 33 | - | expression tag |
| Lys 34 | - | expression tag |
| Gln 35 | - | expression tag |
| Val 36 | - | expression tag |
| Tyr 37 | - | expression tag |
| Arg 38 | - | expression tag |
| Ala 39 | - | expression tag |
| Thr 40 | - | expression tag |
| His 41 | - | expression tag |
| Arg 42 | - | expression tag |
| Leu 43 | - | expression tag |
| Leu 44 | - | expression tag |
| Leu 45 | - | expression tag |
| Leu 46 | - | expression tag |
| Gly 47 | - | expression tag |
| Ala 48 | - | expression tag |
| Asp 49 | - | expression tag |
| Asn 50 | - | expression tag |
| Ser 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Lys 53 | - | expression tag |
| Ser 54 | - | expression tag |
| Thr 55 | - | expression tag |
| Ile 56 | - | expression tag |
| Val 57 | - | expression tag |
| Lys 58 | - | expression tag |
| Gln 59 | - | expression tag |
| Met 60 | - | expression tag |
| Arg 61 | - | expression tag |
| Ile 193 | - | expression tag |
| Leu 194 | - | expression tag |
| His 195 | - | expression tag |
| Gly 196 | - | expression tag |
| Gly 197 | - | expression tag |
| Ser 198 | - | expression tag |
| Gly 199 | - | expression tag |
| Gly 200 | - | expression tag |
| Ser 201 | - | expression tag |
| Gly 202 | - | expression tag |
| Gly 203 | - | expression tag |
| Asp 249 | Ala 140 | conflict |
| Asp 252 | Ser 143 | conflict |
| - | Met 146 | deletion |
| - | Val 147 | deletion |
| - | Ile 148 | deletion |
| - | Arg 149 | deletion |
| - | Glu 150 | deletion |
| - | Asp 151 | deletion |
| - | Asn 152 | deletion |
| - | Gln 153 | deletion |
| - | Thr 154 | deletion |
| - | Asn 155 | deletion |
| Ala 372 | Ile 263 | conflict |
| Ile 375 | Val 266 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met -29 | - | initiating methionine |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Glu -21 | - | expression tag |
| Val -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Phe -18 | - | expression tag |
| Gln -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Gln -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Arg -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 130615.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 150.2 | |
| All* | Total formula weight | 130765.3 |
