8UY0

Consensus olfactory receptor consOR2 bound to S-carvone and in complex with mini-Gs trimeric protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0004984	molecular_function	olfactory receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0016020	cellular_component	membrane
X	0003924	molecular_function	GTPase activity
X	0005525	molecular_function	GTP binding
X	0007186	biological_process	G protein-coupled receptor signaling pathway
X	0019001	molecular_function	guanyl nucleotide binding
X	0031683	molecular_function	G-protein beta/gamma-subunit complex binding
Y	0001750	cellular_component	photoreceptor outer segment
Y	0003924	molecular_function	GTPase activity
Y	0005515	molecular_function	protein binding
Y	0005737	cellular_component	cytoplasm
Y	0005765	cellular_component	lysosomal membrane
Y	0005829	cellular_component	cytosol
Y	0005834	cellular_component	heterotrimeric G-protein complex
Y	0005886	cellular_component	plasma membrane
Y	0007165	biological_process	signal transduction
Y	0007186	biological_process	G protein-coupled receptor signaling pathway
Y	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
Y	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
Y	0007213	biological_process	G protein-coupled acetylcholine receptor signaling pathway
Y	0007265	biological_process	Ras protein signal transduction
Y	0008283	biological_process	cell population proliferation
Y	0016020	cellular_component	membrane
Y	0030159	molecular_function	signaling receptor complex adaptor activity
Y	0044877	molecular_function	protein-containing complex binding
Y	0045202	cellular_component	synapse
Y	0050909	biological_process	sensory perception of taste
Y	0051020	molecular_function	GTPase binding
Y	0060041	biological_process	retina development in camera-type eye
Y	0070062	cellular_component	extracellular exosome
Y	0071380	biological_process	cellular response to prostaglandin E stimulus
Y	0071870	biological_process	cellular response to catecholamine stimulus
Y	0097381	cellular_component	photoreceptor disc membrane
Y	1903561	cellular_component	extracellular vesicle
Z	0005515	molecular_function	protein binding
Z	0005834	cellular_component	heterotrimeric G-protein complex
Z	0005886	cellular_component	plasma membrane
Z	0007165	biological_process	signal transduction
Z	0007186	biological_process	G protein-coupled receptor signaling pathway
Z	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
Z	0016020	cellular_component	membrane
Z	0031681	molecular_function	G-protein beta-subunit binding
Z	0045202	cellular_component	synapse
Z	0048144	biological_process	fibroblast proliferation
Z	0070062	cellular_component	extracellular exosome
Z	0071380	biological_process	cellular response to prostaglandin E stimulus
Z	0071870	biological_process	cellular response to catecholamine stimulus

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. TEClLLAVMAYDRYVaI

Chain	Residue	Details
A	THR109-ILE125

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS

Chain	Residue	Details
Y	LEU70-SER84
Y	ILE157-ILE171
Y	LEU285-ALA299

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P04896

Chain	Residue	Details
X	THR204
X	ASP223
X	LEU302
X	PHE376

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
X	HIS362

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Chain	Residue	Details
X	ASP310

---