8UX1

Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3	polymer	136	15405.0	2	UniProt (A0A653DHJ5) Pfam (PF00125) UniProt (by SIFTS) (P02299) In PDB	Drosophila melanogaster (fruit fly)
2	B, F	Histone H4	polymer	104	11521.6	2	UniProt (P84040) Pfam (PF15511) In PDB	Drosophila melanogaster (fruit fly)
3	C, G	Histone H2A	polymer	124	13388.7	2	UniProt (P84051) Pfam (PF00125) Pfam (PF16211) In PDB	Drosophila melanogaster (fruit fly)
4	D, H	Histone H2B	polymer	125	13897.3	2	UniProt (P02283) Pfam (PF00125) In PDB	Drosophila melanogaster (fruit fly)
5	I	153-bp Widom 601 DNA forward strand	polymer	153	47457.2	1		synthetic construct
6	J	153-bp Widom 601 DNA reverse strand	polymer	153	46998.9	1		synthetic construct
7	K	GTP-binding nuclear protein Ran	polymer	216	24456.1	1	UniProt (P62826) Pfam (PF00071) In PDB	Homo sapiens (human)	Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein
8	L	Regulator of chromosome condensation	polymer	420	44893.8	1	UniProt (P18754) Pfam (PF00415) In PDB	Homo sapiens (human)

Sequence modifications

B, F: 1 - 102 (UniProt: P84040)

PDB	External Database	Details
Met -1	-	initiating methionine
Ile 0	-	expression tag

D, H: -1 - 122 (UniProt: P02283)

PDB	External Database	Details
Gly -2	-	expression tag
Ile 0	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	272231.3
All*	Total formula weight	272231.3

*Water molecules are not included.