8UX1
Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3 | polymer | 136 | 15405.0 | 2 | UniProt (A0A653DHJ5) Pfam (PF00125) UniProt (by SIFTS) (P02299) | Drosophila melanogaster (fruit fly) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 104 | 11521.6 | 2 | UniProt (P84040) Pfam (PF15511) | Drosophila melanogaster (fruit fly) | |
| 3 | C, G (C, G) | Histone H2A | polymer | 124 | 13388.7 | 2 | UniProt (P84051) Pfam (PF00125) Pfam (PF16211) | Drosophila melanogaster (fruit fly) | |
| 4 | D, H (D, H) | Histone H2B | polymer | 125 | 13897.3 | 2 | UniProt (P02283) Pfam (PF00125) | Drosophila melanogaster (fruit fly) | |
| 5 | I (I) | 153-bp Widom 601 DNA forward strand | polymer | 153 | 47457.2 | 1 | synthetic construct | ||
| 6 | J (J) | 153-bp Widom 601 DNA reverse strand | polymer | 153 | 46998.9 | 1 | synthetic construct | ||
| 7 | K (K) | GTP-binding nuclear protein Ran | polymer | 216 | 24456.1 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 8 | L (L) | Regulator of chromosome condensation | polymer | 420 | 44893.8 | 1 | UniProt (P18754) Pfam (PF00415) | Homo sapiens (human) |
Sequence modifications
B, F: 1 - 102 (UniProt: P84040)
D, H: -1 - 122 (UniProt: P02283)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Ile 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ile 0 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 272231.3 | |
| All* | Total formula weight | 272231.3 |
