8UVW
Crystal structure of RAD51-BRCA2 Cter complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Breast cancer type 2 susceptibility protein, DNA repair protein RAD51 homolog 1 fusion | polymer | 297 | 32212.6 | 1 | UniProt (P51587) UniProt (Q06609) Pfam (PF00634) Pfam (PF08423) | Homo sapiens (Human) | Fanconi anemia group D1 protein,HsRAD51,hRAD51,RAD51 homolog A |
| 2 | B (D) | DNA repair protein RAD51 homolog 1,Breast cancer type 2 susceptibility protein | polymer | 289 | 31215.4 | 1 | UniProt (Q06609) UniProt (P51587) Pfam (PF08423) Pfam (PF22687) | Homo sapiens (human) | Fanconi anemia group D1 protein |
| 3 | C, G (B, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | D, H (B, D) | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 2 | Chemie (BEF) | |||
| 5 | E, F (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | I, J (B, D) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
B: 1517 - 1547 (UniProt: P51587)
B: 85 - 339 (UniProt: Q06609)
D: 97 - 339 (UniProt: Q06609)
D: 3270 - 3305 (UniProt: P51587)
| PDB | External Database | Details |
|---|---|---|
| Gly 1515 | - | expression tag |
| Ser 1516 | - | expression tag |
| Thr 76 | - | linker |
| Gly 77 | - | linker |
| Ser 78 | - | linker |
| Thr 79 | - | linker |
| Gly 80 | - | linker |
| Ser 81 | - | linker |
| Thr 82 | - | linker |
| Gly 83 | - | linker |
| Ser 84 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 319 | Cys 319 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 208 | Ser 208 | engineered mutation |
| Asp 209 | Ala 209 | engineered mutation |
| Ser 319 | Cys 319 | engineered mutation |
| Ser 3260 | - | linker |
| Ser 3261 | - | linker |
| Asp 3262 | - | linker |
| Ser 3263 | - | linker |
| Ser 3264 | - | linker |
| Leu 3265 | - | linker |
| Ser 3266 | - | linker |
| Ser 3267 | - | linker |
| Pro 3268 | - | linker |
| Ser 3269 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 3287 | Cys 3287 | engineered mutation |
| Ala 3304 | Cys 3304 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63428.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1110.6 | |
| All* | Total formula weight | 64538.5 |
