8UVW

Crystal structure of RAD51-BRCA2 Cter complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000150	molecular_function	DNA strand exchange activity
B	0000724	biological_process	double-strand break repair via homologous recombination
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005524	molecular_function	ATP binding
B	0006259	biological_process	DNA metabolic process
B	0006281	biological_process	DNA repair
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
B	1990426	biological_process	mitotic recombination-dependent replication fork processing
D	0000150	molecular_function	DNA strand exchange activity
D	0000724	biological_process	double-strand break repair via homologous recombination
D	0003677	molecular_function	DNA binding
D	0003690	molecular_function	double-stranded DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005524	molecular_function	ATP binding
D	0006259	biological_process	DNA metabolic process
D	0006281	biological_process	DNA repair
D	0008094	molecular_function	ATP-dependent activity, acting on DNA
D	0140664	molecular_function	ATP-dependent DNA damage sensor activity
D	1990426	biological_process	mitotic recombination-dependent replication fork processing

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	146
Details	Region: {"description":"Interaction with PALB2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	Motif: {"description":"Nuclear export signal; masked by the interaction with BRCA2","evidences":[{"source":"PubMed","id":"24013206","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29507080","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NWL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by CHEK1","evidences":[{"source":"PubMed","id":"15665856","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by CDK1 and CDK2","evidences":[{"source":"PubMed","id":"15800615","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---