8UVW
Crystal structure of RAD51-BRCA2 Cter complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000150 | molecular_function | DNA strand exchange activity |
| B | 0000724 | biological_process | double-strand break repair via homologous recombination |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003690 | molecular_function | double-stranded DNA binding |
| B | 0003697 | molecular_function | single-stranded DNA binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006281 | biological_process | DNA repair |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| B | 1990426 | biological_process | mitotic recombination-dependent replication fork processing |
| D | 0000150 | molecular_function | DNA strand exchange activity |
| D | 0000724 | biological_process | double-strand break repair via homologous recombination |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003690 | molecular_function | double-stranded DNA binding |
| D | 0003697 | molecular_function | single-stranded DNA binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006259 | biological_process | DNA metabolic process |
| D | 0006281 | biological_process | DNA repair |
| D | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| D | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| D | 1990426 | biological_process | mitotic recombination-dependent replication fork processing |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 146 |
| Details | Region: {"description":"Interaction with PALB2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Motif: {"description":"Nuclear export signal; masked by the interaction with BRCA2","evidences":[{"source":"PubMed","id":"24013206","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29507080","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5NWL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by CHEK1","evidences":[{"source":"PubMed","id":"15665856","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CDK1 and CDK2","evidences":[{"source":"PubMed","id":"15800615","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17515903","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
