8UV2

Human p97/VCP structure with a triazole inhibitor (NSC799462/hexamer)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Transitional endoplasmic reticulum ATPase	polymer	806	89436.8	6	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862)	Homo sapiens (human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	G, H, J, K, M... (A, B, C, D, E...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	12	Chemie (ADP)
3	I, L, O, R, U... (A, B, C, D, E...)	3-(4-{[(4P)-5-{[(1R)-cyclohex-2-en-1-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}-2,6-difluorophenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate	non-polymer		594.7	6	Chemie (XKM)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	536620.9
Non-Polymers*	Number of molecules	18
	Total formula weight	8694.5
All*	Total formula weight	545315.4

*Water molecules are not included.