8UV1

Structure of TDP1 complexed with compound IB01

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosyl-DNA phosphodiesterase 1	polymer	461	52126.3	2	UniProt (Q9NUW8) Pfam (PF06087)	Homo sapiens (human)	Tyr-DNA phosphodiesterase 1
2	C, D, E, G, H... (A, B)	8-(fluorosulfonyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid	non-polymer		271.2	7	Chemie (XK6)
3	F, K (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	L, M (A, B)	water	water		18.0	571	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104252.7
Non-Polymers*	Number of molecules	9
	Total formula weight	2022.7
All*	Total formula weight	106275.4

*Water molecules are not included.