8UV1
Structure of TDP1 complexed with compound IB01
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:12470949, ECO:0000269|PubMed:15111055 |
| Chain | Residue | Details |
| A | HIS263 | |
| B | HIS263 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:12470949, ECO:0000269|PubMed:15111055 |
| Chain | Residue | Details |
| A | HIS493 | |
| B | HIS493 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12470949 |
| Chain | Residue | Details |
| A | LYS265 | |
| A | LYS495 | |
| B | LYS265 | |
| B | LYS495 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Interaction with DNA => ECO:0000269|PubMed:12470949 |
| Chain | Residue | Details |
| A | SER518 | |
| B | SER518 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| A | SER148 | |
| B | SER148 |
