8UUQ
Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, F | Fusion glycoprotein F0 | polymer | 112 | 12498.8 | 3 | UniProt (Q786F3) In PDB | Measles virus strain Ichinose-B95a | |
2 | C, E, G | Fusion glycoprotein F0 | polymer | 420 | 44898.8 | 3 | UniProt (Q786F3) Pfam (PF00523) In PDB | Measles virus strain Ichinose-B95a | |
3 | M, N, O | [FIP-HRC]2-PEG11 | polymer | 4 | 503.5 | 3 | BIRD (PRD_002539) | synthetic construct | |
4 | B, H, J, L | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 4 | In PDB GlyTouCan (G15407YE) | |||
5 | I, K | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
6 | A, D, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
7 | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
C, E, G: 113 - 495 (UniProt: Q786F3)
PDB | External Database | Details |
---|---|---|
Gly 170 | Glu 170 | engineered mutation |
Gly 455 | Glu 455 | engineered mutation |
Gly 496 | - | expression tag |
Val 497 | - | expression tag |
Asp 498 | - | expression tag |
Asp 499 | - | expression tag |
Asp 500 | - | expression tag |
Asp 501 | - | expression tag |
Lys 502 | - | expression tag |
Ala 503 | - | expression tag |
Gly 504 | - | expression tag |
Trp 505 | - | expression tag |
Ser 506 | - | expression tag |
His 507 | - | expression tag |
Pro 508 | - | expression tag |
Gln 509 | - | expression tag |
Phe 510 | - | expression tag |
Glu 511 | - | expression tag |
Lys 512 | - | expression tag |
Gly 513 | - | expression tag |
Gly 514 | - | expression tag |
Gly 515 | - | expression tag |
Ser 516 | - | expression tag |
Gly 517 | - | expression tag |
Gly 518 | - | expression tag |
Gly 519 | - | expression tag |
Ser 520 | - | expression tag |
Gly 521 | - | expression tag |
Gly 522 | - | expression tag |
Gly 523 | - | expression tag |
Ser 524 | - | expression tag |
Trp 525 | - | expression tag |
Ser 526 | - | expression tag |
His 527 | - | expression tag |
Pro 528 | - | expression tag |
Gln 529 | - | expression tag |
Phe 530 | - | expression tag |
Glu 531 | - | expression tag |
Lys 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 173703.4 | |
Branched | Number of molecules | 6 |
Total formula weight | 4167.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 178534.8 |