8UUD
BCX2627 complexed with human FVIIa and soluble Tissue Factor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Factor VII light chain | polymer | 142 | 16359.8 | 1 | UniProt (P08709) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | |
| 2 | B (H) | Coagulation factor VII Heavy Chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | C (T) | Tissue factor | polymer | 75 | 8715.8 | 1 | UniProt (P13726) Pfam (PF01108) | Homo sapiens (human) | |
| 4 | D (U) | Tissue factor | polymer | 116 | 13354.9 | 1 | UniProt (P13726) Pfam (PF09294) | Homo sapiens (human) | |
| 5 | E (L) | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 6 | F (L) | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
| 7 | G, H, I, J, K... (L, H) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 8 | P (H) | (1P)-2'-[(4-carbamimidoylphenyl)carbamoyl]-4'-ethenyl-4-[(2-methylpropyl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid | non-polymer | 484.5 | 1 | Chemie (XGX) | |||
| 9 | Q, R, S, T (L, H, T, U) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
U: 91 - 210 (UniProt: P13726)
| PDB | External Database | Details |
|---|---|---|
| - | Lys 191 | deletion |
| - | Ser 192 | deletion |
| - | Ser 193 | deletion |
| - | Ser 194 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 66533.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1189.6 | |
| All* | Total formula weight | 67723.3 |
