8URF
Crystal Structure of human ASGR2 CRD (Carbohydrate Recognition Domain) bound to 8G8 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | 8G8 Fab Light Chain | polymer | 214 | 23529.0 | 1 | Homo sapiens (human) | ||
| 2 | B (H) | 8G8 Fab Heavy Chain | polymer | 232 | 24972.8 | 1 | Homo sapiens (human) | ||
| 3 | C (A) | Asialoglycoprotein receptor 2 | polymer | 159 | 18822.5 | 1 | UniProt (P07307) Pfam (PF00059) | Homo sapiens (human) | |
| 4 | D, E, I, J, K (L, H, A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | F, G, H (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | L (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | M, N, O (L, H, A) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 177 - 311 (UniProt: P07307)
| PDB | External Database | Details |
|---|---|---|
| Ser 312 | - | expression tag |
| Gly 313 | - | expression tag |
| Arg 314 | - | expression tag |
| Gly 315 | - | expression tag |
| Leu 316 | - | expression tag |
| Asn 317 | - | expression tag |
| Asp 318 | - | expression tag |
| Ile 319 | - | expression tag |
| Phe 320 | - | expression tag |
| Glu 321 | - | expression tag |
| Ala 322 | - | expression tag |
| Gln 323 | - | expression tag |
| Lys 324 | - | expression tag |
| Ile 325 | - | expression tag |
| Glu 326 | - | expression tag |
| Trp 327 | - | expression tag |
| His 328 | - | expression tag |
| Glu 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67324.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 616.2 | |
| All* | Total formula weight | 67940.5 |
