8UQN

PLCb3-Gaq complex on membranes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Guanine nucleotide-binding protein G(q) subunit alpha	polymer	355	41676.4	1	UniProt (P50148) Pfam (PF00503)	Homo sapiens (human)
2	B (B)	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	polymer	1234	139104.7	1	UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703)	Homo sapiens (human)	Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3
3	C (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
4	D (A)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	1	Chemie (ALF) PubChem (5311325)
5	E (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
6	F (B)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA) PubChem (271)
7	G (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A: 7 - 359 (UniProt: P50148)

PDB	External Database	Details
Gly 5	-	expression tag
Pro 6	-	expression tag

B: 10 - 1234 (UniProt: Q01970)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Ala 3	-	expression tag
Met 4	-	expression tag
Asp 5	-	expression tag
Pro 6	-	expression tag
Glu 7	-	expression tag
Phe 8	-	expression tag
Met 9	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	180781.1
Non-Polymers*	Number of molecules	4
	Total formula weight	610.6
All*	Total formula weight	181391.7

*Water molecules are not included.