8UQN

PLCb3-Gaq complex on membranes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Guanine nucleotide-binding protein G(q) subunit alpha	polymer	355	41676.4	1	UniProt (P50148) Pfam (PF00503) In PDB	Homo sapiens (human)
2	B	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	polymer	1234	139104.7	1	UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) In PDB	Homo sapiens (human)	Phosphoinositide phospholipase C-beta-3,Phospholipase C-beta-3,PLC-beta-3
3	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
4	A	TETRAFLUOROALUMINATE ION	non-polymer		103.0	1	Chemie (ALF)
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	B	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
7		water	water		18.0	1	Chemie (HOH)

Sequence modifications

A: 7 - 359 (UniProt: P50148)

PDB	External Database	Details
Gly 5	-	expression tag
Pro 6	-	expression tag

B: 10 - 1234 (UniProt: Q01970)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Ala 3	-	expression tag
Met 4	-	expression tag
Asp 5	-	expression tag
Pro 6	-	expression tag
Glu 7	-	expression tag
Phe 8	-	expression tag
Met 9	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	180781.1
Non-Polymers*	Number of molecules	4
	Total formula weight	610.6
All*	Total formula weight	181391.7

*Water molecules are not included.