8UQB
Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E | polymer | 455 | 50040.3 | 1 | UniProt (Q8IYW5) UniProt (P61077) UniProt (Q16778) UniProt (P04908) Pfam (PF14447) Pfam (PF00179) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (human) | |
2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 1 - 94 (UniProt: Q8IYW5)
A: 1002 - 1147 (UniProt: P61077)
A: 2033 - 2123 (UniProt: Q16778)
A: 3012 - 3105 (UniProt: P04908)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
His 0 | - | expression tag |
Ser 95 | - | linker |
Gly 96 | - | linker |
Ser 97 | - | linker |
Gly 98 | - | linker |
Ser 99 | - | linker |
Gly 100 | - | linker |
Ser 101 | - | linker |
PDB | External Database | Details |
---|---|---|
Lys 1085 | Cys 85 | engineered mutation |
Gly 1148 | - | linker |
Gly 1149 | - | linker |
Ser 1150 | - | linker |
Gly 1151 | - | linker |
Gly 1152 | - | linker |
Gly 1153 | - | linker |
Ser 1154 | - | linker |
Gly 1155 | - | linker |
Gly 1156 | - | linker |
Ser 1157 | - | linker |
Gly 1158 | - | linker |
Gly 1159 | - | linker |
Ser 1160 | - | linker |
Gly 1161 | - | linker |
Gly 1162 | - | linker |
Ser 1163 | - | linker |
Gly 1164 | - | linker |
Ser 1165 | - | linker |
Gly 1166 | - | linker |
Ser 1167 | - | linker |
PDB | External Database | Details |
---|---|---|
Ser 3011 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 50040.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 272.6 | |
All* | Total formula weight | 50312.9 |