8UMZ

Crystal Structure of Engineered Mouse Protocadherin-15 EC4-EC7 Connection

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protocadherin-15 EC4-EC7	polymer	230	25921.7	2	UniProt (Q99PJ1) Pfam (PF00028)	Mus musculus (house mouse)
2	C, D, E, F, G... (A, B)	CALCIUM ION	non-polymer		40.1	10	Chemie (CA)
3	H, N (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	O, P (A, B)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A, B: 366 - 484 (UniProt: Q99PJ1)

PDB	External Database	Details
Met 365	-	initiating methionine

A, B: 485 - 586 (UniProt: Q99PJ1)

PDB	External Database	Details
Leu 587	-	expression tag
Glu 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag
His 593	-	expression tag
His 594	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51843.4
Non-Polymers*	Number of molecules	12
	Total formula weight	446.8
All*	Total formula weight	52290.2

*Water molecules are not included.