8ULK
Prefusion RSV F bound by neutralizing antibody 1G12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fusion glycoprotein F2 | polymer | 72 | 8173.3 | 3 | UniProt (P03420) | Human respiratory syncytial virus A2 | |
| 2 | D, F, H (D, H, F) | 1G12 Fab heavy chain | polymer | 235 | 25313.2 | 3 | Homo sapiens | ||
| 3 | E, G, I (E, L, G) | 1G12 Fab light chain | polymer | 214 | 23316.1 | 3 | Homo sapiens | ||
| 4 | J, K, L (I, J, K) | Fusion glycoprotein F0,Fibritin | polymer | 414 | 45609.1 | 3 | UniProt (A0A088S9A7) UniProt (P10104) Pfam (PF00523) | Respiratory syncytial virus A2 | Collar protein,Whisker antigen control protein |
Sequence modifications
I, J, K: 137 - 513 (UniProt: A0A088S9A7)
I, J, K: 518 - 544 (UniProt: P10104)
| PDB | External Database | Details |
|---|---|---|
| Cys 155 | Ser 155 | conflict |
| Phe 190 | Ser 190 | conflict |
| Leu 207 | Val 207 | conflict |
| Cys 290 | Ser 290 | conflict |
| Ser 514 | - | linker |
| Ala 515 | - | linker |
| Ile 516 | - | linker |
| Gly 517 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 539 | Phe 479 | conflict |
| Gly 545 | - | expression tag |
| Gly 546 | - | expression tag |
| Leu 547 | - | expression tag |
| Val 548 | - | expression tag |
| Pro 549 | - | expression tag |
| Arg 550 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 307235.5 | |
| All* | Total formula weight | 307235.5 |
