8ULJ

Prefusion RSV F bound by neutralizing antibody 2E08

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fusion glycoprotein F2	polymer	79	8873.0	1	UniProt (P03420)	Respiratory syncytial virus A2	F2
2	B (L)	2E08 Fab Light Chain	polymer	214	23336.8	1		Homo sapiens
3	C (H)	2E08 Fab Heavy Chain	polymer	242	25919.1	1		Homo sapiens
4	D (B)	Fusion glycoprotein F0,Fibritin	polymer	414	45609.1	1	UniProt (A0A088S9A7) UniProt (P10104) Pfam (PF00523)	Respiratory syncytial virus A2	Collar protein,Whisker antigen control protein

Sequence modifications

A: 26 - 104 (UniProt: P03420)

PDB	External Database	Details
Ala 102	Pro 102	conflict

B: 137 - 513 (UniProt: A0A088S9A7)

PDB	External Database	Details
Cys 155	Ser 155	conflict
Phe 190	Ser 190	conflict
Leu 207	Val 207	conflict
Cys 290	Ser 290	conflict
Ser 514	-	linker
Ala 515	-	linker
Ile 516	-	linker
Gly 517	-	linker

B: 518 - 544 (UniProt: P10104)

PDB	External Database	Details
Leu 539	Phe 479	conflict
Gly 545	-	expression tag
Gly 546	-	expression tag
Leu 547	-	expression tag
Val 548	-	expression tag
Pro 549	-	expression tag
Arg 550	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	103738.1
All*	Total formula weight	103738.1

*Water molecules are not included.