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8UII

Cryo-EM map of human clamp-clamp loader ATAD5-RFC-closed PCNA complex in intermediate state 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATPase family AAA domain-containing protein 5polymer1844207902.31UniProt (Q96QE3)
Pfam (PF00004)
Homo sapiens (human)
2B
(B)
Replication factor C subunit 2polymer35439203.21UniProt (P35250)
Pfam (PF00004)
Pfam (PF08542)
Homo sapiens (human)Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RFC40
3C
(C)
Replication factor C subunit 5polymer34038545.51UniProt (P40937)
Pfam (PF00004)
Pfam (PF21960)
Pfam (PF08542)
Homo sapiens (human)Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RFC36
4D
(D)
Replication factor C subunit 4polymer36339735.71UniProt (P35249)
Pfam (PF00004)
Pfam (PF21960)
Pfam (PF08542)
Homo sapiens (human)
5E
(E)
Replication factor C subunit 3polymer35640614.31UniProt (P40938)
Pfam (PF13177)
Pfam (PF21960)
Pfam (PF22534)
Homo sapiens (human)Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RFC38
6F, G, H
(F, G, H)
Proliferating cell nuclear antigenpolymer26128795.83UniProt (P12004)
Pfam (PF00705)
Pfam (PF02747)
Homo sapiens (human)PCNA,Cyclin
7I, K, M, O
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
8J, L, N, P
(A, B, C, D)
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERnon-polymer523.24Chemie (AGS)
9Q
(E)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight452388.4
Non-Polymers*Number of molecules9
Total formula weight2617.4
All*Total formula weight455005.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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