8UI8

Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATPase family AAA domain-containing protein 5	polymer	1032	116421.1	1	UniProt (Q96QE3) Pfam (PF00004) In PDB	Homo sapiens (human)
2	B	Replication factor C subunit 2	polymer	354	39203.2	1	UniProt (P35250) Pfam (PF00004) Pfam (PF08542) In PDB	Homo sapiens (human)	Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RFC40
3	C	Replication factor C subunit 5	polymer	340	38545.5	1	UniProt (P40937) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542) In PDB	Homo sapiens (human)	Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RFC36
4	D	Replication factor C subunit 4	polymer	363	39735.7	1	UniProt (P35249) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542) In PDB	Homo sapiens (human)
5	E	Replication factor C subunit 3	polymer	356	40614.3	1	UniProt (P40938) Pfam (PF13177) Pfam (PF21960) Pfam (PF22534) In PDB	Homo sapiens (human)	Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RFC38
6	F, G	Proliferating cell nuclear antigen	polymer	261	28795.8	2	UniProt (P12004) Pfam (PF00705) Pfam (PF02747) In PDB	Homo sapiens (human)	PCNA,Cyclin
7	A, B, C	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
8	A, B, C	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	3	Chemie (AGS)
9	D, E	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	332111.4
Non-Polymers*	Number of molecules	8
	Total formula weight	2497.1
All*	Total formula weight	334608.4

*Water molecules are not included.