8UGO
Structure of the complex between Human LIAS and H-protein in the presence of 5'-deoxyadenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, B, D) | Lipoyl synthase, mitochondrial | polymer | 368 | 41457.5 | 3 | UniProt (O43766) Pfam (PF16881) Pfam (PF04055) | Homo sapiens (human) | Lipoate synthase,LS,Lip-syn,Lipoic acid synthase |
| 2 | B, D, F (E, C, F) | Glycine cleavage system H protein, mitochondrial | polymer | 173 | 18902.5 | 3 | UniProt (P23434) Pfam (PF01597) | Homo sapiens (human) | Lipoic acid-containing protein |
| 3 | G, N, W (A, B, D) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 3 | Chemie (5AD) | |||
| 4 | H, O, V (A, B, D) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 3 | Chemie (SF4) | |||
| 5 | I, P, X (A, B, D) | FE3-S4 CLUSTER | non-polymer | 295.8 | 3 | Chemie (F3S) | |||
| 6 | J (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | K (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | L, S, Y (A, B, D) | METHIONINE | non-polymer | 149.2 | 3 | Chemie (MET) | |||
| 9 | M, U, Z (E, C, F) | 6-THIOOCTANOIC ACID | non-polymer | 176.3 | 3 | Chemie (YVI) | |||
| 10 | Q (B) | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
| 11 | R (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 12 | T (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 13 | AA, BA, CA, DA, EA... (A, E, B, C, D...) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B, D: 1 - 368 (UniProt: O43766)
| PDB | External Database | Details |
|---|---|---|
| Ala 368 | Lys 368 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 181079.9 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4632.5 | |
| All* | Total formula weight | 185712.3 |
