8UET

In-situ complex I, Deactive class02

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (1A)	NADH-ubiquinone oxidoreductase chain 3	polymer	115	13026.5	1	UniProt (O79880) Pfam (PF00507)	Sus scrofa (pig)	NADH dehydrogenase subunit 3
2	B (1B)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	polymer	258	28500.2	1	UniProt (A0A4X1VVS8) Pfam (PF01058)	Sus scrofa (pig)
3	C (1C)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	polymer	264	30154.3	1	UniProt (A0A286ZNN4) Pfam (PF00329)	Sus scrofa (pig)
4	D (1D)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	polymer	476	54168.1	1	UniProt (A0A8D0QM68) Pfam (PF00346)	Sus scrofa (pig)
5	E (1E)	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	polymer	249	27439.5	1	UniProt (A0A4X1VRV3) Pfam (PF01257)	Sus scrofa (pig)
6	F (1F)	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	polymer	464	50637.8	1	UniProt (A0A4X1SZP7) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589)	Sus scrofa (pig)
7	G (1G)	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	polymer	727	79627.4	1	UniProt (A0A287ARY3) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) Pfam (PF13510)	Sus scrofa (pig)
8	H (1H)	NADH-ubiquinone oxidoreductase chain 1	polymer	318	35619.4	1	UniProt (A0A0U1RS44) Pfam (PF00146)	Sus scrofa (pig)
9	I (1I)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	polymer	239	27135.0	1	UniProt (A0A286ZUN9) Pfam (PF12838)	Sus scrofa (pig)
10	J (1J)	NADH-ubiquinone oxidoreductase chain 6	polymer	175	19049.3	1	UniProt (O79882) Pfam (PF00499)	Sus scrofa (pig)	NADH dehydrogenase subunit 6
11	K (1K)	NADH-ubiquinone oxidoreductase chain 4L	polymer	98	10855.3	1	UniProt (P56632) Pfam (PF00420)	Sus scrofa (pig)	NADH dehydrogenase subunit 4L
12	L (1L)	NADH-ubiquinone oxidoreductase chain 5	polymer	606	68723.5	1	UniProt (Q9TDR1) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455)	Sus scrofa (pig)	NADH dehydrogenase subunit 5
13	M (1M)	NADH-ubiquinone oxidoreductase chain 4	polymer	459	51887.4	1	UniProt (O79881) Pfam (PF01059) Pfam (PF00361)	Sus scrofa (pig)	NADH dehydrogenase subunit 4
14	N (1N)	NADH-ubiquinone oxidoreductase chain 2	polymer	347	39105.5	1	UniProt (O79875) Pfam (PF00361) Pfam (PF06444)	Sus scrofa (pig)	NADH dehydrogenase subunit 2
15	O (1O)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	polymer	357	40476.1	1	UniProt (F1SIS9) Pfam (PF01712)	Sus scrofa (pig)
16	P (1P)	NADH:ubiquinone oxidoreductase subunit A9	polymer	377	42606.3	1	UniProt (A0A4X1ULW2) Pfam (PF01370)	Sus scrofa (pig)
17	Q (1Q)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	polymer	175	19746.5	1	UniProt (A0A4X1SN37) Pfam (PF04800)	Sus scrofa (pig)
18	R (1R)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	polymer	123	13349.0	1	UniProt (A0A4X1THU2) Pfam (PF10276)	Sus scrofa (pig)
19	S (1S)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	polymer	99	11099.8	1	UniProt (A0A8D1FN21) Pfam (PF05047)	Sus scrofa (pig)
20	T, U (1T, 1U)	NADH:ubiquinone oxidoreductase subunit AB1	polymer	156	17338.2	2	UniProt (A0A8D1KH26) Pfam (PF00550)	Sus scrofa (pig)
21	V (1V)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X1	polymer	116	13321.6	1	UniProt (A0A8D0UWW0) Pfam (PF04716)	Sus scrofa (pig)
22	W (1W)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	polymer	128	14953.3	1	UniProt (A0A480VKQ8) Pfam (PF05347)	Sus scrofa (pig)
23	X (1X)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	polymer	172	20064.1	1	UniProt (A0A8D0K6B5) Pfam (PF06747)	Sus scrofa (pig)
24	Y (1Y)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	polymer	141	14686.9	1	UniProt (I3LGM4) Pfam (PF02466)	Sus scrofa (pig)
25	Z (1Z)	NADH:ubiquinone oxidoreductase subunit A13	polymer	144	16911.6	1	UniProt (A0A8D0K655) Pfam (PF06212)	Sus scrofa (pig)
26	AA (1a)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	polymer	70	8034.4	1	UniProt (A0A8D0TJQ4) Pfam (PF15879)	Sus scrofa (pig)
27	BA (1b)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	polymer	84	9225.6	1	UniProt (A0A4X1VQ42) Pfam (PF14987)	Sus scrofa (pig)
28	CA (1c)	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial	polymer	76	8664.1	1	UniProt (A0A8D1EYQ2)	Sus scrofa (pig)
29	DA (1d)	NADH dehydrogenase [ubiquinone] 1 subunit C2	polymer	123	14353.7	1	UniProt (A0A480JRW3) Pfam (PF06374)	Sus scrofa (pig)
30	EA (1e)	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	polymer	106	12506.6	1	UniProt (A0A4X1VX77) Pfam (PF10200)	Sus scrofa (pig)
31	FA (1f)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [Sus scrofa]	polymer	135	15371.9	1	UniProt (A0A8D1IZ33) Pfam (PF08040)	Sus scrofa (pig)
32	GA (1g)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	polymer	154	17384.7	1	UniProt (A0A8D1EYI7) Pfam (PF10183)	Sus scrofa (pig)
33	HA (1h)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	polymer	189	21587.0	1	UniProt (F1SGC6) Pfam (PF09781)	Sus scrofa (pig)
34	IA (1i)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	polymer	128	15645.2	1	UniProt (A0A4X1UIV8) Pfam (PF09782)	Sus scrofa (pig)
35	JA (1j)	NADH:ubiquinone oxidoreductase subunit B2	polymer	105	11939.4	1	UniProt (A0A8D1G9F4) Pfam (PF14813)	Sus scrofa (pig)
36	KA (1k)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	polymer	98	11128.5	1	UniProt (A0A4X1VD84) Pfam (PF08122)	Sus scrofa (pig)
37	LA (1l)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	polymer	186	21658.4	1	UniProt (B8Y651) Pfam (PF05821)	Sus scrofa (pig)
38	MA (1m)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	polymer	129	15117.4	1	UniProt (A0A4X1T6M0) Pfam (PF07225)	Sus scrofa (pig)
39	NA (1n)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	polymer	179	21864.9	1	UniProt (K7GSE5) Pfam (PF05347)	Sus scrofa (pig)
40	OA (1o)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	polymer	137	16487.9	1	UniProt (F1SCH1) Pfam (PF05676)	Sus scrofa (pig)
41	PA (1p)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	polymer	176	20944.8	1	UniProt (A0A8D0R7A9) Pfam (PF10249)	Sus scrofa (pig)
42	QA (1q)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	polymer	145	17162.4	1	UniProt (F1SQP4) Pfam (PF05071)	Sus scrofa (pig)
43	RA (1r)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	polymer	114	12674.6	1	UniProt (A0A8W4F7N8) Pfam (PF07347)	Sus scrofa (pig)	Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a
44	SA (1s)	NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial	polymer	471	48217.8	1	UniProt (A0A4X1TE42) Pfam (PF15880)	Sus scrofa (pig)
45	IB, JB, KB, NB, TA... (1L, 1N, 1A, 1Y)	1,2-Distearoyl-sn-glycerophosphoethanolamine	non-polymer		748.1	6	Chemie (3PE)
46	DB, EB, UA, XA, YA... (1I, 1B, 1F, 1G)	IRON/SULFUR CLUSTER	non-polymer		351.6	6	Chemie (SF4)
47	AB, VA (1G, 1E)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
48	WA (1F)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)
49	BB (1G)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
50	CB, FB, GB, MB, WB (1H, 1I, 1J, 1M, 1f)	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	5	Chemie (PC1)
51	HB (1L)	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR)
52	LB (1M)	(1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE	non-polymer		751.0	1	Chemie (PGT)
53	OB, VB (1N, 1a)	CARDIOLIPIN	non-polymer		1464.0	2	Chemie (CDL)
54	PB (1O)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
55	QB (1O)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
56	RB (1P)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
57	SB (1R)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
58	TB, XB (1W, 1n)	~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate	non-polymer		584.7	2	Chemie (EHZ)

Sequence modifications

1C: -35 - 228 (UniProt: A0A286ZNN4)

PDB	External Database	Details
Gln 104	Arg 140	conflict
Gly 154	Asp 190	conflict

1D: -32 - 430 (UniProt: A0A8D0QM68)

PDB	External Database	Details
Gly 0	Glu 33	conflict

1d: -1 - 120 (UniProt: A0A480JRW3)

PDB	External Database	Details
Ace -2	-	acetylation

1f: -48 - 57 (UniProt: A0A8D1IZ33)

PDB	External Database	Details
Met -77	-	initiating methionine
Ala -76	-	expression tag
Ala -75	-	expression tag
Ala -74	-	expression tag
Ile -73	-	expression tag
Leu -72	-	expression tag
Lys -71	-	expression tag
Leu -70	-	expression tag
Glu -69	-	expression tag
Glu -68	-	expression tag
Thr -67	-	expression tag
Arg -66	-	expression tag
Gly -65	-	expression tag
Gly -64	-	expression tag
Gly -63	-	expression tag
Glu -62	-	expression tag
Lys -61	-	expression tag
Cys -60	-	expression tag
Asp -59	-	expression tag
Lys -58	-	expression tag
Asn -57	-	expression tag
Gln -56	-	expression tag
Gly -55	-	expression tag
Val -54	-	expression tag
Lys -53	-	expression tag
Gly -52	-	expression tag
Arg -51	-	expression tag
Arg -50	-	expression tag
Phe -49	-	expression tag

1r: -1 - 112 (UniProt: A0A8W4F7N8)

PDB	External Database	Details
Ace 0	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	45
	Total formula weight	1097790.1
Non-Polymers*	Number of molecules	31
	Total formula weight	17831.2
All*	Total formula weight	1115621.4

*Water molecules are not included.