8UCT
Crystal structure of TcPINK1 in complex with PRT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase Pink1, mitochondrial | polymer | 455 | 51032.3 | 1 | UniProt (D6WMX4) Pfam (PF00069) | Tribolium castaneum (red flour beetle) | |
| 2 | B (A) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | non-polymer | 393.4 | 1 | Chemie (3YT) | |||
| 5 | F (A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A: 121 - 570 (UniProt: D6WMX4)
| PDB | External Database | Details |
|---|---|---|
| Gly 116 | - | expression tag |
| Pro 117 | - | expression tag |
| Leu 118 | - | expression tag |
| Gly 119 | - | expression tag |
| Ser 120 | - | expression tag |
| Ala 131 | Trp 131 | engineered mutation |
| Ala 142 | Trp 142 | engineered mutation |
| Ala 225 | Tyr 225 | engineered mutation |
| Ala 378 | Tyr 378 | engineered mutation |
| Ala 401 | Phe 401 | engineered mutation |
| Ala 437 | Phe 437 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51032.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 739.8 | |
| All* | Total formula weight | 51772.1 |
