8UCC
IRAK4 in complex with compound 20
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34578.0 | 1 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | B (B) | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34498.0 | 1 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 3 | C, D (A, B) | (4S)-2-[(1R,4s)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-N-[(8S)-6-methylpyrazolo[1,5-a]pyrimidin-3-yl]-7-[(propan-2-yl)oxy]imidazo[1,2-a]pyrimidine-6-carboxamide | non-polymer | 447.5 | 2 | Chemie (WFQ) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69075.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 895.0 | |
| All* | Total formula weight | 69970.9 |
